Closed Loop Medicine (CLM) is the global leader in the development of single prescription drug plus digital therapy (DTx) combination products developed to optimise dosing on an individual level with linked behaviour therapy to improve patient outcomes. CLM was founded by an experienced team of healthcare professionals, entrepreneurs and life scientists with experience of both drug and software development, as well as extensive health system innovation experience. CLM has two products in development for hypertension and insomnia. It has further products in its pipeline for a wide portfolio of chronic diseases. CLM ensures that both patient and clinician are at the centre of its products design and development.